NDC80 Antikörper
Kurzübersicht für NDC80 Antikörper (ABIN7116759)
Target
Alle NDC80 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- NDC80 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- NDC80 homolog, kinetochore complex component
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))
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Andere Bezeichnung
- NDC80
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Hintergrund
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Synonyms: Kinetochore protein NDC80 homolog|Highly expressed in cancer protein|Kinetochore protein Hec1 (HsHec1)|Kinetochore-associated protein 2|Retinoblastoma-associated protein HEC|NDC80|HEC|HEC1|KNTC2
Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity(PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore(PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules(PubMed:23085020).
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Molekulargewicht
- 76 kDa
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Gen-ID
- 10403
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UniProt
- O14777
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Pathways
- Maintenance of Protein Location
Target
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